There are trillions of cells in the body and when cancer occurs in the body it is because abnormal cells in the body are produced and the growth of those cells are uncontrollable. Mar 11, 2015 more periorbital ecchymoses of neuroblastoma months old at diagnosis 1 month into therapy 15. Neuroblastoma ireland pdf ppt case reports symptoms. Median age at presentation 23 months, peak 04 years. A free powerpoint ppt presentation displayed as a flash slide show on id. Nov 10, 2016 neuroblastoma is the most common extracranial solid tumour occurring in childhood and has a diverse clinical presentation and course depending on the tumour biology. Rare presentation of a congenital neuroblastoma ignatius edwin dsouza md mrcpch 1, ramesh chandra patidar md 1, ravichandran mani md 1, mahmoud shamseldeen ms md 1, joyce jose md 2 dermatology online journal 15 11. When these cells start to grow out of control, they form a. Constitutional symptoms include failure to thrive, fever, hypertension, bouts of sweating and pallor. W e report the case of 26 year old man who presented with a. If you continue browsing the site, you agree to the use of cookies on this website. Olfactory neuroblastoma esthesioneuroblastoma presenting. This incidence is fairly uniform throughout the world, at least for industrialized nations.
This collection includes unique designs and results that you can use freely for your own presentation needs. Business presentation templates free downloads slidebean. Neuroblastoma neuroblasts at least 50% of the tumor mass undifferentiated neuroblastoma undifferentiated neuroblastoma poorly differentiated neuroblastoma poorly differentiated neuroblastoma differentiating neuroblastoma differentiating neuroblastoma at least 5% cells less than 5% cells all cells 30. Osteosarcoma is the most common primary bone tumor diagnosed in childhood ppt. Bartlett missouri primo inervento chirurgico di asportazione di nbl 470 gr. These features are typical of a large neuroblastoma, which classically envelop and displace vessels, something wilms tumors do not. View and download powerpoint presentations on pediatric renal tumors ppt. However, experience shows that as many as 5060% of children with highrisk neuroblastoma will eventually suffer a relapse. Neuroblastoma powerpoint ppt presentations powershow. See epidemiology, pathogenesis, and pathology of neuroblastoma and treatment and prognosis of neuroblastoma.
Neuroblastoma is a malignant tumour of neural crest cells which give rise to the. Ppt neuroblastoma powerpoint presentation free to download. Two cases of neuroblastoma presenting to the emergency. Except for case reports, case series and studies including fewer than 20. Discuss the basics of clinical presentation, diagnostics, and. Mri abdomen reveals a well defined mass lesion in right suprarenal region.
Gi clinical case conference gi clinical case conference case presentation 12 yo boy with history of neuroblastoma presents with 1 years of. Download figure open in new tab download powerpoint. In treatment for neuroblastoma childrens oncology group. Neuroblastoma is sometimes caused by a gene mutation change passed from the parent to the child. Department of pediatrics, gulf medical college hospital, ajman, uae 2.
We report the case of 26 year old man who presented with a retroperitoneal neuroblastoma. Neuroblastoma nb is the most common extracranial solid malignancy in children but rarely described in adults, being 10% of all cases diagnosed after the first decade of life. Each free presentation is unique, which is why there are so many uniquely designed presentation templates to express each persons creativity and style. Characteristic site of mass lesion and typical correlative clinical features led to presumptive diagnosis of neuroblastoma. Unusual cns presentation of neuroblastoma springerlink. Remote work advice from the largest allremote company. Department of pathology, gulf medical university, ajman, uae.
Neuroblastoma is slightly more common in boys than in girls, with a maletofemale sex ratio of 1. Find powerpoint presentations and slides using the power of, find free presentations research about pediatric renal tumors ppt. Neuroblastoma articles case reports symptoms treatment, norway. Care of children with neuroblastoma is provided by a multidisciplinary team involving pediatric oncology, radiation oncologists, surgeons, and anesthesiologists, as well as nurse practitioners, nurses, pharmacists, psychologists, and physical and occupational therapists dedicated to the special needs of these children. Therefore, pediatricians should be familiar with clinical presentations that should prompt appropriate and timely referral. Late presentation of neuroblastoma with brain metastases. Neuroblastoma is the most common extracranial solid tumor in children, accounting for 7% to 8% of all childhood cancers. Hypertension is an uncommon sign of the disease and is generally caused by renal artery compression, not catecholamine excess. Using microsoft powerpoint or office 365, you can easily create engaging presentations.
The prevalence is about 1 case per 7,000 live births. Scribd is the worlds largest social reading and publishing site. Free business powerpoint templates collection includes high quality corporate templates, management technique presentations and many other business associated powerpoint templates. In case 2 the patient presented with a limp and left hip pain. Abdominal tumors in children free download as powerpoint presentation. More than half these patients are diagnosed in the first year of life. Pediatricians play a pivotal role in the diagnosis of neuroblastoma and as such should be aware of. Storia 1864 virchow propose che il neuroblastoma nbl era di origine neurale 1891 marchand descrisse le cellule del nbl, sono simili a quella del s. Neuroblastoma nb is a type of cancer that forms in certain types of nerve tissue.
Under this section, you can get immediate access to some of the free powerpoint templates available in our catalog. From pitch decks to client proposals, investor updates and a company profile template. Case presentation history brought to pediatrician with a rightsided abdominal mass on visit, mass was appreciated by pmd who immediately obtained a kub and abdominal us which revealed a large 12cm cystic lesion involving right kidney. A case of metastatic high grade neuroblastoma with. A 22yearold woman presented to her local district hospital with leftsided abdominal pain. Genomewide analysis of neuroblastoma from these rare familial cases has identified a genetic defect involved in these cases.
We report a rare case of neuroblastoma in a 3yearold child presenting classical oral manifestations such as bilateral palatal swelling, rolled border ulcer on the. In 8 of these 21 cases, cushings syndrome was the initial presentation of the underlying tumour. If neuroblastoma comes back after initial treatment, it is known as a recurrence or relapse. But only 10% of cases occur in people older than 5 years of age and less than 2% cases were over 18yearold. If you have any other questions or feel like there is some information that i did not cover. The presentation of pelvic neuroblastoma is different from that of tumors arising in other parts of the abdomen. Treatment of recurrent neuroblastoma depends on many factors, including the initial risk group, where the cancer recurs, and what treatments have been used. One recent series from france identified 52 cases of neuroblastoma over a 10year period and found 40 of the cases to be abdominal, eight to be thoracic, one cervical, and three in the pelvis. In this article, we illustrate the extraabdominal clinical presentations and imaging findings of seven cases of abdominal neuroblastoma diagnosed in our hospital, a tertiary children cancer centre in hong kong, over the past 10 years. Most common extracranial solid tumor of childhood over half of the children present with metastatic disease arise from cells of the neural crest that form the adrenal medulla and sympathetic ganglia.
Signs and symptoms of neuroblastoma vary with site of presentation. The epidemiology, pathogenesis, pathology, treatment, and prognosis of neuroblastoma are presented separately. Gi clinical case conference case presentation 12 yo boy with history of. Our free powerpoint backgrounds and presentation templates are very easy to customize and edit for your presentation needs. On the other hand, an absence of detected chromosomal imbalances in neuroblastoma biopsies is difficult to interpret because it is unclear whether this situation truly reflects the tumour genome or if it is due to. Neuroblastoma my lecture 2011 chemotherapy radiation. Aug, 2012 we report the use of salvage radiosurgery to manage an aggressive olfactory neuroblastoma esthesioneuroblastoma with multiple recurrences and intracranial extension. Signs and symptoms of neuroblastoma include a lump in the abdomen, neck, or chest or bone. Download free powerpoint themes and powerpoint backgrounds for your presentations. She denied any urinary or gastrointestinal symptoms.
Currently, there are no standard treatment guidelines for adult nb patients. Neuroblastoma my lecture 2011 free ebook download as powerpoint presentation. The case of a neuroblastoma presenting symptoms of ec at birth is exceptional and deserves to be reported. Neuroblastoma articles case reports symptoms treatment, ireland. O ur collection of free business powerpoint templates. Olfactory neuroblastoma and sphenoidal sinus ectopic pituitary adenoma are known for causing such false positive gradients.
A 43yearold caucasian woman presented 11 years ago with progressive nasal blockage and headaches. Thousands of ppt templates easy to edit with highquality slides, created by top designers around the world. Recent advances in treatment options and identification of. It most frequently starts from one of the adrenal glands but can also develop in the neck, chest, abdomen, or spine. An uncommon presentation of neuroblastoma case reports. Neuroblastoma presenting with symptoms of epidural. Childrens oncology group cog most commonly used international neuroblastoma risk group inrg both take into account the following prognostic factors. The clinical presentation of neuroblastoma reflects the tumors primary location and the extent. She was referred to a tertiary referral centre and given the size of the adrenal mass. Five to 10 % of children with neuroblastoma present with symptoms of epidural compression ec. In children with intermediate or lowrisk neuroblastoma, relapses occur in only 515% of cases.
Neuroblastoma is one of the most common paediatric malignancies. Neuroblastoma is a common tumor of childhood, usually occurring in children under 4 years of age 1. Peroperatively lesion was found to be neuroblastoma. Download the best free powerpoint templates to create modern presentations. The major clinical staging systems international neuroblastoma staging system inss based on the evans staging system is shown in table 1. Clinical presentation, evaluation, and management of.
Neuroblastoma is a disease in which malignant cancer cells form in neuroblasts immature nerve tissue in the adrenal glands, neck, chest, or spinal cord. This video was made for a project for my lifespan 3 class, i do not own any of the images or material. Neuroblastoma is the most common extracranial solid cancer in childhood and the most common cancer in infancy. Neuroblastoma is most commonly diagnosed in children under the age of 5 years old, but can be diagnosed in older children as well. Neuroblastoma treatment pdqpatient version national. And theyre ready for you to use in your powerpoint presentations the moment you need them. The sunburst pattern of the calvarial metastasis noted in this case is rarely seen with neuroblastoma. Neuroblastoma is a pediatric neoplasm that is the most common cancer diagnosed during infancy. Alsufyani medical intern, taif university school of medicine, taif, saudi arabia. Generally, symptoms include abdominal pain, emesis, weight loss, anorexia, fatigue, and bone pain. While it accounts for 7% of all childhood malignancies, neuroblastoma accounts for 10% of childhood cancer mortality. C m chu, frcr, 1 d d rasalkar, frcr, 1 y j hu, md, 3 f w t cheng, mrcp, 2 c k li, frcp, 2 and w c w chu, md 1.
Neuroblastoma norway pdf ppt case reports symptoms. We report a case of a 10year old child who initially presented with a large calvarial mass representing a solitary site of metastasis from an occult adrenal neuroblastoma. The clinical presentation, diagnosis, and staging evaluation of neuroblastoma will be presented here. Apr 04, 2017 this video was made for a project for my lifespan 3 class, i do not own any of the images or material. Symptoms may include bone pain, a lump in the abdomen, neck, or. Clinical presentation imaging fetal neuroblastoma is normally diagnosed during the third trimester at an average age of 33 weeks, although there are reports of sonographic diagnosis as early as 23 weeks. Oct 09, 2017 neuroblastoma has been known to occur in the setting of other disorders that are linked to abnormal development of neural crest tissues, such as hirschsprung disease or central congenital hypoventilation syndrome. Slides can be edited in slidebean, with a fillinthe blank interface that uses artificial intelligence to arrange the content. Age and stage at initial presentation remain two most important factors that influence outcome.
Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Osteosarcoma is the most common primary bone tumor diagnosed in childhood and adolescence, with peak incidence from ages 1216. Clinical presentation, evaluation, and management of neuroblastoma. Wright introdusse il termine di neuroblastoma 1914 w. Risk groups two systems for determining risk group are available. Clinical presentations and imaging findings of neuroblastoma.
Till date, no case of neuroblastoma of palate in patient case report highlights the classical oral and clinical manifestations of a rare case of neuroblastoma of the oral cavity in a 3yearold male child. If neuroblastoma is going to relapse at all, it usually does so within the first two years after the end of treatment. Neuroblastoma is the second most common malignant solid tumor in the pediatric population. A case of metastatic high grade neuroblastoma with undetected. The case presentation is followed by a general discussion with an emphasis on the diagnosis, treatment, and followup of neuroblastoma and its association with pregnancy. Detection of somatic genetic alterations in this tumour is instrumental for its risk stratification and treatment.
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